Denounced to the anti–Christian authorities by other doctors during the persections of Diocletian. At trial he offered a contest to see whose prayers would cure the incurable – his or the pagan priests’. The pagans failed to help the man, a palsied paralytic, but Pantaleon cured the man by mentioning the name Jesus. Many of the witnesses converted.
The authorities tried to bribe him to denounce the faith, but failed. They then threatened him; that failed. They followed up the threats with torture. When that failed, he was executed. Martyr. One of the Fourteen Holy Helpers.
He was nailed to a tree and beheaded c.305 and a phial of his blood is preserved at Constantinople, and is reported to become liquid and bubble on his Feast Day
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